PAI-1 4G/5G polymorphism contributes to cancer susceptibility: evidence from meta-analysis.

BACKGROUND: The plasminogen activator inhibitor-1 (PAI-1) is expressed in many cancer cell types and allows the modulation of cancer growth, invasion and angiogenesis. To date, studies investigated the association between a functional polymorphism in PAI-1 (4G/5G) and risk of cancer have shown inclu...

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Bibliographic Details
Main Authors: Shangqian Wang, Qiang Cao, Xiaoxiang Wang, Bingjie Li, Min Tang, Wanqing Yuan, Jianzheng Fang, Jian Qian, Chao Qin, Wei Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3577655?pdf=render