Pathogenic Mitochondria DNA Mutations: Current Detection Tools and Interventions

Mitochondria are best known for their role in energy production, and they are the only mammalian organelles that contain their own genomes. The mitochondrial genome mutation rate is reported to be 10−17 times higher compared to nuclear genomes as a result of oxidative damage caused by reac...

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Bibliographic Details
Main Authors: Mohd Fazirul Mustafa, Sharida Fakurazi, Maizaton Atmadini Abdullah, Sandra Maniam
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/2/192