Protease nexin-1 expression is altered in human breast cancer

<p>Abstract</p> <p>Background</p> <p>Urokinase-type Plasminogen Activator (uPA), a serine protease, plays a pivotal role in human breast cancer metastasis by mediating the degradation of extracellular matrix proteins and promoting cell motility. In more advanced breast...

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Bibliographic Details
Main Authors: Griffith Jeffrey K, Heaphy Christopher M, Hines William C, Candia Britny J, Orlando Robert A
Format: Article
Language:English
Published: BMC 2006-05-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/6/1/16