Metformin Activates the Protective Effects of the AMPK Pathway in Acute Lung Injury Caused by Paraquat Poisoning

Metformin Activates the Protective Effects of the AMPK Pathway in Acute Lung Injury Caused by Paraquat Poisoning

Objective. To observe whether metformin (MET) plays a protective role in acute lung injury (ALI) induced by paraquat (PQ) poisoning in rats by activating the AMPK/NF-κB signaling pathway. Methods. PQ exposure was used to construct a rat model of ALI and a model of acute type II alveolar epithelial c...

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Bibliographic Details
Main Authors: Liaozhang Wu, Yifang Cen, Menglong Feng, Yanna Zhou, Hui Tang, Xueli Liao, Yanze Wang, Min Wang, Manhong Zhou
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/1709718

Internet

http://dx.doi.org/10.1155/2019/1709718

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