Ambiguity in logic-based models of gene regulatory networks: An integrative multi-perturbation analysis.

Most studies of gene regulatory network (GRN) inference have focused extensively on identifying the interaction map of the GRNs. However, in order to predict the cellular behavior, modeling the GRN in terms of logic circuits, i.e., Boolean networks, is necessary. The perturbation techniques, e.g., k...

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Bibliographic Details
Main Authors: Amir Reza Alizad-Rahvar, Mehdi Sadeghi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6245684?pdf=render