Identification of MicroRNA-92a-3p as an Essential Regulator of Tubular Epithelial Cell Pyroptosis by Targeting Nrf1 via HO-1

Identification of MicroRNA-92a-3p as an Essential Regulator of Tubular Epithelial Cell Pyroptosis by Targeting Nrf1 via HO-1

Renal ischemia–reperfusion injury (IRI) is a major cause of acute kidney injury (AKI) and has no effective treatment. Exploring the molecular mechanisms of renal IRI is critical for the prevention of AKI and its evolution to chronic kidney disease and end-stage renal disease. The aim of the present...

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Bibliographic Details
Main Authors: Renhe Wang, Haijun Zhao, Yingyu Zhang, Hai Zhu, Qiuju Su, Haiyan Qi, Jun Deng, Chengcheng Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Genetics
Subjects:
renal ischemia–reperfusion injury
miR-92a-3p
Nrf1
pyroptosis
tubular epithelial cell
HO-1
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.616947/full

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https://www.frontiersin.org/articles/10.3389/fgene.2020.616947/full

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