Kunitz-type protease inhibitor as a vaccine candidate against schistosomiasis mansoni

Objective: The aim of this study was to develop a vaccine against schistosomiasis, which is a major challenge due to the complex lifecycle of the causative schistosome parasite. Methods: SmKI-1 is a 16-kDa Kunitz-type protease inhibitor present in the excretory–secretory products and tegument of adu...

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Bibliographic Details
Main Authors: Shiwanthi L. Ranasinghe, Mary Duke, Marina Harvie, Donald P. McManus
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:International Journal of Infectious Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971217302813