Pharmacokinetics of anticoagulant edoxaban in overdose in a Japanese patient transported to hospital

Pharmacokinetics of anticoagulant edoxaban in overdose in a Japanese patient transported to hospital

Abstract Background The anticoagulant edoxaban is used clinically at doses of 30–60 mg/day; however, we experienced a patient who had taken an overdose of edoxaban of 750 mg. We investigated the pharmacokinetics of edoxaban in this patient by using liquid chromatography–tandem spectrometry to estima...

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Bibliographic Details
Main Authors: Koichiro Adachi, Jumpei Tuchiya, Satoru Beppu, Kei Nishiyama, Makiko Shimizu, Hiroshi Yamazaki
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Pharmaceutical Health Care and Sciences
Subjects:
Anticoagulants
Pharmacokinetic modeling
Overdose
Online Access:http://link.springer.com/article/10.1186/s40780-020-00176-6

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http://link.springer.com/article/10.1186/s40780-020-00176-6

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