Cytotoxic Activity of Semi-Synthetic Derivatives of Elatol and Isoobtusol

Cytotoxic Activity of Semi-Synthetic Derivatives of Elatol and Isoobtusol

In the present study, the in vitro cytotoxic effects of six semi-synthetic derivatives of elatol (1) and isoobtusol (2) were investigated. Chemical modifications were performed on the hydroxyl groups aiming to get derivatives of different polarity, namely the hemisuccinate, carbamate and sulfamate....

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Bibliographic Details
Main Authors: Eloir P. Schenkel, Fernando J. Durán, Cláudia M. O. Simões, Miriam Falkenberg, Jorge A. Palermo, Maria V. Mañalich Arana, Cíntia Lhullier, Izabella T. Silva, Lara A. Zimmermann, Karen L. Lang
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:Marine Drugs
Subjects:
elatol
isoobtusol
sesquiterpenes
synthesis
cytotoxic activity
Online Access:http://www.mdpi.com/1660-3397/10/10/2254

Internet

http://www.mdpi.com/1660-3397/10/10/2254

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