MicroRNA-135a Protects Against Ethanol-Induced Apoptosis in Neural Crest Cells and Craniofacial Defects in Zebrafish by Modulating the Siah1/p38/p53 Pathway

MicroRNA-135a Protects Against Ethanol-Induced Apoptosis in Neural Crest Cells and Craniofacial Defects in Zebrafish by Modulating the Siah1/p38/p53 Pathway

MicroRNAs (miRNAs) are small non-coding RNAs that are involved in various biological processes, including apoptosis, by regulating gene expression. This study was designed to test the hypothesis that ethanol-induced downregulation of miR-135a contributes to ethanol-induced apoptosis in neural crest...

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Bibliographic Details
Main Authors: Fuqiang Yuan, Yang Yun, Huadong Fan, Yihong Li, Lanhai Lu, Jie Liu, Wenke Feng, Shao-yu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
miRNA-135a
ethanol
apoptosis
neural crest cells
Siah1
craniofacial defects
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.583959/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.583959/full

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