A novel role for DNA methyltransferase 1 in regulating oocyte cytoplasmic maturation in pigs.

Maternal factors are required for oocyte maturation and embryo development. To better understand the role of DNA methyltransferase 1 (Dnmt1) in oocyte maturation and embryo development, small interfering RNA (siRNA) was conducted in porcine oocytes. In this study, our results showed that Dnmt1 local...

Full description

Bibliographic Details
Main Authors: Yanjun Huan, Bingteng Xie, Shichao Liu, Qingran Kong, Zhonghua Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0127512