Comprehensive in vitro pro‐arrhythmic assays demonstrate that omecamtiv mecarbil has low pro‐arrhythmic risk
Abstract Omecamtiv mecarbil (OM) is a myosin activator (myotrope), developed as a potential therapeutic agent for heart failure with reduced ejection fraction. To characterize the potential pro‐arrhythmic risk of this novel sarcomere activator, we evaluated OM in a series of International Conference...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-07-01
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Series: | Clinical and Translational Science |
Online Access: | https://doi.org/10.1111/cts.13039 |