Ethanol-mediated upregulation of APOA1 gene expression in HepG2 cells is independent of de novo lipid biosynthesis

Abstract Background Moderate alcohol intake in human increases HDL-cholesterol, and has protective effects against cardiovascular disease (CVD). Although de novo lipid synthesis inhibitors are highly effective in lowering total and LDL-cholesterol they have only modest effects on raising HDL-C. A be...

Full description

Bibliographic Details
Main Authors: Youcef Khodja, Mark E. Samuels
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Lipids in Health and Disease
Subjects:
HDL
Online Access:http://link.springer.com/article/10.1186/s12944-020-01309-4