Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation

Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation

Translational frameshifting is a mechanism that expands the coding capabilities of mRNA. Here, structures of 70S ribosome complexes with GTPase elongation factor G (EF-G), a +1-frameshifting-prone mRNA and tRNAs reveal the cooperation between the ribosome and EF-G to induce +1 frameshifting during t...

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Bibliographic Details
Main Authors: Gabriel Demo, Howard B. Gamper, Anna B. Loveland, Isao Masuda, Christine E. Carbone, Egor Svidritskiy, Ya-Ming Hou, Andrei A. Korostelev
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24911-1

Internet

https://doi.org/10.1038/s41467-021-24911-1

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