M2-polarized macrophages promote metastatic behavior of Lewis lung carcinoma cells by inducing vascular endothelial growth factor-C expression

M2-polarized macrophages promote metastatic behavior of Lewis lung carcinoma cells by inducing vascular endothelial growth factor-C expression

OBJECTIVES: Tumor-associated macrophages that generally exhibit an alternatively activated (M2) phenotype have been linked to tumor progression and metastasis. However, the role of M2-polarized macrophages in the growth and metastasis of lung adenocarcinoma remains enigmatic. The aim of this study w...

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Bibliographic Details
Main Authors: Bicheng Zhang, Yafei Zhang, Guoqing Yao, Juan Gao, Bo Yang, Yong Zhao, Zhiguo Rao, Jianfei Gao
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2012-08-01
Series:Clinics
Subjects:
M2-polarized macrophages
Lewis lung carcinoma
Proliferation
Migration
Lymphangiogenesis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322012000800008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322012000800008

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