Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses

Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses

Summary: Loss of p53 function contributes to the development of many cancers. While cell-autonomous consequences of p53 mutation have been studied extensively, the role of p53 in regulating the anti-tumor immune response is still poorly understood. Here, we show that loss of p53 in cancer cells modu...

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Bibliographic Details
Main Authors: Julianna Blagih, Fabio Zani, Probir Chakravarty, Marc Hennequart, Steven Pilley, Sebastijan Hobor, Andreas K. Hock, Josephine B. Walton, Jennifer P. Morton, Eva Gronroos, Susan Mason, Ming Yang, Iain McNeish, Charles Swanton, Karen Blyth, Karen H. Vousden
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471931678X

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http://www.sciencedirect.com/science/article/pii/S221112471931678X

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