Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system.
Obesity is a growing epidemic characterized by excess fat storage in adipocytes. Although lipoprotein receptors play important roles in lipid uptake, their role in controlling food intake and obesity is not known. Here we show that the lipoprotein receptor LRP1 regulates leptin signaling and energy...
Main Authors: | Qiang Liu, Juan Zhang, Celina Zerbinatti, Yan Zhan, Benedict J Kolber, Joachim Herz, Louis J Muglia, Guojun Bu |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
|
Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC3019112?pdf=render |
Similar Items
-
Correction: Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System.
by: Qiang Liu, et al.
Published: (2019-06-01) -
LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis
by: Xunde Xian, et al.
Published: (2017-11-01) -
Central Regulation of Energy Homeostasis by Leptin.
by: Sato, Noriko
Published: (2014) -
Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Abeta42 uptake and lysosomal trafficking.
by: Rodrigo A Fuentealba, et al.
Published: (2010-07-01) -
Leptin: role over central nervous system in epilepsy
by: Laura Mora-Muñoz, et al.
Published: (2018-09-01)