Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system.

Obesity is a growing epidemic characterized by excess fat storage in adipocytes. Although lipoprotein receptors play important roles in lipid uptake, their role in controlling food intake and obesity is not known. Here we show that the lipoprotein receptor LRP1 regulates leptin signaling and energy...

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Bibliographic Details
Main Authors: Qiang Liu, Juan Zhang, Celina Zerbinatti, Yan Zhan, Benedict J Kolber, Joachim Herz, Louis J Muglia, Guojun Bu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3019112?pdf=render