Effects of STAT3 Gene Silencing and Rapamycin on Apoptosis in Hepatocarcinoma Cells

<p>The PI3K/Akt/mTOR and JAK/STAT3 signaling pathways are important for regulating apoptosis, and are frequently activated in cancers. In this study, we targeted STAT3 and mTOR in human hepatocellular carcinoma Bel-7402 cells and examined the subsequent alterations in cellular apoptosis. The e...

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Bibliographic Details
Main Author: Yi Zhang, Jun-Wei Zhang, Guo-Yue Lv, Shu-Li Xie, Guang-Yi Wang
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v09p0216.htm