The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells

Summary: The coronavirus disease 2019 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus, is a global health issue with unprecedented challenges for public health. SARS-CoV-2 primarily infects cells of the respiratory tract via spike glycoprotein binding to...

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Bibliographic Details
Main Authors: Xiaodong Zhuang, Senko Tsukuda, Florian Wrensch, Peter A.C. Wing, Mirjam Schilling, James M. Harris, Helene Borrmann, Sophie B. Morgan, Jennifer L. Cane, Laurent Mailly, Nazia Thakur, Carina Conceicao, Harshmeena Sanghani, Laura Heydmann, Charlotte Bach, Anna Ashton, Steven Walsh, Tiong Kit Tan, Lisa Schimanski, Kuan-Ying A. Huang, Catherine Schuster, Koichi Watashi, Timothy S.C. Hinks, Aarti Jagannath, Sridhar R. Vausdevan, Dalan Bailey, Thomas F. Baumert, Jane A. McKeating
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221011123