Isoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epithelia.

Isoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epithelia.

Adenovirus is an important respiratory pathogen. Adenovirus fiber from most serotypes co-opts the Coxsackie-Adenovirus Receptor (CAR) to bind and enter cells. However, CAR is a cell adhesion molecule localized on the basolateral membrane of polarized epithelia. Separation from the lumen of the airwa...

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Bibliographic Details
Main Authors: Katherine J D A Excoffon, Nicholas D Gansemer, Matthew E Mobily, Philip H Karp, Kalpaj R Parekh, Joseph Zabner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2845650?pdf=render

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http://europepmc.org/articles/PMC2845650?pdf=render

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