Orthotopic Bone Formation by Streamlined Engineering and Devitalization of Human Hypertrophic Cartilage

Orthotopic Bone Formation by Streamlined Engineering and Devitalization of Human Hypertrophic Cartilage

Most bones of the human body form and heal through endochondral ossification, whereby hypertrophic cartilage (HyC) is formed and subsequently remodeled into bone. We previously demonstrated that HyC can be engineered from human mesenchymal stromal cells (hMSC), and subsequently devitalized by apopto...

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Bibliographic Details
Main Authors: Sébastien Pigeot, Paul Emile Bourgine, Jaquiery Claude, Celeste Scotti, Adam Papadimitropoulos, Atanas Todorov, Christian Epple, Giuseppe M. Peretti, Ivan Martin
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
bioreactors
bone repair
endochondral ossification
hypertrophic cartilage
regenerative medicine
Online Access:https://www.mdpi.com/1422-0067/21/19/7233

Internet

https://www.mdpi.com/1422-0067/21/19/7233

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