Emerging Epigenetic Therapeutic Targets in Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a genetically heterogeneous malignancy for which treatment options have been largely limited to cytotoxic chemotherapy for the past four decades. Next-generation sequencing and other approaches have identified a spectrum of genomic and epigenomic alterations that cont...

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Bibliographic Details
Main Authors: Bettina Wingelhofer, Tim C. P. Somervaille
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Oncology
Subjects:
AML
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00850/full