Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transition.

Endothelial cell (EC) plasticity in pathological settings has recently been recognized as a driver of disease progression. Endothelial-to-mesenchymal transition (EndMT), in which ECs acquire mesenchymal properties, has been described for a wide range of pathologies, including cancer. However, the me...

Full description

Bibliographic Details
Main Authors: Nao Nagai, Hiroto Ohguchi, Ryo Nakaki, Yoshihiro Matsumura, Yasuharu Kanki, Juro Sakai, Hiroyuki Aburatani, Takashi Minami
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1007826