Lipocalin 2 regulates expression of MHC class I molecules in Mycobacterium tuberculosis-infected dendritic cells via ROS production

Lipocalin 2 regulates expression of MHC class I molecules in Mycobacterium tuberculosis-infected dendritic cells via ROS production

Abstract Background Iron has important roles as an essential nutrient for all life forms and as an effector of the host defense mechanism against pathogenic infection. Lipocalin 2 (LCN2), an innate immune protein, plays a crucial role in iron transport and inflammation. In the present study, we exam...

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Bibliographic Details
Main Authors: Ji-Ae Choi, Soo-Na Cho, Junghwan Lee, Sang-Hun Son, Doan Tam Nguyen, Seong-Ahn Lee, Chang-Hwa Song
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Cell & Bioscience
Subjects:
Lipocalin 2
Mycobacterium tuberculosis
MHC class I
Reactive oxygen species
Online Access:https://doi.org/10.1186/s13578-021-00686-2

Internet

https://doi.org/10.1186/s13578-021-00686-2

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