ATPIF1 maintains normal mitochondrial structure which is impaired by CCM3 deficiency in endothelial cells

Abstract Background Numerous signaling pathways have been demonstrated experimentally to affect the pathogenesis of cerebral cavernous malformations (CCM), a disease that can be caused by CCM3 deficiency. However, the understanding of the CCM progression is still limited. The objective of the presen...

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Bibliographic Details
Main Authors: Kang Wang, Haixuan Chen, Zhongyang Zhou, Haifeng Zhang, Huanjiao Jenny Zhou, Wang Min
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-020-00514-z