Prohibitin 1 Acts As a Negative Regulator of Wingless/Integrated‐Beta‐Catenin Signaling in Murine Liver and Human Liver Cancer Cells

Prohibitin 1 Acts As a Negative Regulator of Wingless/Integrated‐Beta‐Catenin Signaling in Murine Liver and Human Liver Cancer Cells

Prohibitin1 (PHB1) is a mitochondrial chaperone with diverse functions that include cell proliferation, apoptosis, and mitochondrial homoeostasis. Liver‐specific Phb1 knockout (KO) mice develop spontaneous injury and hepatocellular carcinoma (HCC). Our previous work demonstrated that PHB1 negatively...

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Bibliographic Details
Main Authors: Nirmala Mavila, Yuanyuan Tang, Joshua Berlind, Komal Ramani, Jiaohong Wang, José M. Mato, Shelly C. Lu
Format: Article
Language:English
Published: Wiley 2018-12-01
Series:Hepatology Communications
Online Access:https://doi.org/10.1002/hep4.1257

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