Prohibitin 1 Acts As a Negative Regulator of Wingless/Integrated‐Beta‐Catenin Signaling in Murine Liver and Human Liver Cancer Cells
Prohibitin1 (PHB1) is a mitochondrial chaperone with diverse functions that include cell proliferation, apoptosis, and mitochondrial homoeostasis. Liver‐specific Phb1 knockout (KO) mice develop spontaneous injury and hepatocellular carcinoma (HCC). Our previous work demonstrated that PHB1 negatively...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-12-01
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Series: | Hepatology Communications |
Online Access: | https://doi.org/10.1002/hep4.1257 |