Inhibition of DKC1 induces telomere-related senescence and apoptosis in lung adenocarcinoma

Abstract Background Lung cancer is one of the most widely spread cancers in the world and half of the non-small cell lung cancers are lung adenocarcinoma (LUAD). Although there were several drugs been approved for LUAD therapy, a large portion of LUAD still cannot be effectively treated due to lack...

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Bibliographic Details
Main Authors: Guangyan Kan, Ziyang Wang, Chunjie Sheng, Chen Yao, Yizhi Mao, Shuai Chen
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-021-02827-0