Role of Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly

Hepatitis C virus (HCV) glycoproteins E1 and E2 form a heterodimer to constitute viral envelope proteins, which play an essential role in virus entry. E1 does not directly interact with host receptors, and its functions in viral entry are exerted mostly through its interaction with E2 that directly...

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Bibliographic Details
Main Authors: Yimin Tong, Dimitri Lavillette, Qingchao Li, Jin Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
E1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01411/full