Comparison of Monkeypox Virus Clade Kinetics and Pathology within the Prairie Dog Animal Model Using a Serial Sacrifice Study Design

Comparison of Monkeypox Virus Clade Kinetics and Pathology within the Prairie Dog Animal Model Using a Serial Sacrifice Study Design

Monkeypox virus (MPXV) infection of the prairie dog is valuable to studying systemic orthopoxvirus disease. To further characterize differences in MPXV clade pathogenesis, groups of prairie dogs were intranasally infected (8×103 p.f.u.) with Congo Basin (CB) or West African (WA) MPXV, and 28 tissues...

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Main Authors: Christina L. Hutson, Darin S. Carroll, Nadia Gallardo-Romero, Clifton Drew, Sherif R. Zaki, Tamas Nagy, Christine Hughes, Victoria A. Olson, Jeanine Sanders, Nishi Patel, Scott K. Smith, M. Shannon Keckler, Kevin Karem, Inger K. Damon
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/965710

Internet

http://dx.doi.org/10.1155/2015/965710

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