Oligomerization Profile of Human Transthyretin Variants with Distinct Amyloidogenicity
One of the molecular hallmarks of amyloidoses is ordered protein aggregation involving the initial formation of soluble protein oligomers that eventually grow into insoluble fibrils. The identification and characterization of molecular species critical for amyloid fibril formation and disease develo...
Main Authors: | Ana Frangolho, Bruno E. Correia, Daniela C. Vaz, Zaida L. Almeida, Rui M. M. Brito |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/23/5698 |
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