Development of carrier-free nanocrystals of poorly water-soluble drugs by exploring metastable zone of nucleation
There has been increasing interest in research and development of nanocrystals for the delivery of poorly water-soluble drugs that can be directly produced from solution. Compared with traditional carrier-based or encapsulation designs, drug nanocrystals circumvent possible side-effects due to carri...
Main Authors: | Xiaoting Ren, Jianping Qi, Wei Wu, Zongning Yin, Tonglei Li, Yi Lu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
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Series: | Acta Pharmaceutica Sinica B |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383518301229 |
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