Nutlin-3a: A Potential Therapeutic Opportunity for TP53 Wild-Type Ovarian Carcinomas.

Epithelial ovarian cancer is a diverse molecular and clinical disease, yet standard treatment is the same for all subtypes. TP53 mutations represent a node of divergence in epithelial ovarian cancer histologic subtypes and may represent a therapeutic opportunity in subtypes expressing wild type, inc...

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Bibliographic Details
Main Authors: Erin K Crane, Suet-Yan Kwan, Daisy I Izaguirre, Yvonne T M Tsang, Lisa K Mullany, Zhifei Zu, JoAnne S Richards, David M Gershenson, Kwong-Kwok Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0135101