Oxygen-sensing neurons reciprocally regulate peripheral lipid metabolism via neuropeptide signaling in Caenorhabditis elegans.

The mechanisms by which the sensory environment influences metabolic homeostasis remains poorly understood. In this report, we show that oxygen, a potent environmental signal, is an important regulator of whole body lipid metabolism. C. elegans oxygen-sensing neurons reciprocally regulate peripheral...

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Bibliographic Details
Main Authors: Rosalind Hussey, Nicole K Littlejohn, Emily Witham, Erik Vanstrum, Jaleh Mesgarzadeh, Harkaranveer Ratanpal, Supriya Srinivasan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5886693?pdf=render