Exploration of the main sites for the transformation of normal prion protein (PrPC) into pathogenic prion protein (PrPsc)

Exploration of the main sites for the transformation of normal prion protein (PrPC) into pathogenic prion protein (PrPsc)

Introduction: The functions and mechanisms of prion proteins (PrPC) are currently unknown, but most experts believe that deformed or pathogenic prion proteins (PrPSc) originate from PrPC, and that there may be plural main sites for the conversion of normal PrPC into PrPSc. In order to better underst...

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Bibliographic Details
Main Authors: Liu Xi-Lin, Feng Xiao-Li, Wang Guang-Ming, Gong Bin-Bin, Ahmad Waqas, Liu Nan-Nan, Zhang Yuan-Yuan, Yang Li, Ren Hong-Lin, Cui Shu-Sen
Format: Article
Language:English
Published: Sciendo 2017-03-01
Series:Journal of Veterinary Research
Subjects:
mice
brain
prion proteins
myelin sheath
particle aggregation
Online Access:https://doi.org/10.1515/jvetres-2017-0002

Internet

https://doi.org/10.1515/jvetres-2017-0002

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