Emerging patterns of plasmid-host coevolution that stabilize antibiotic resistance

Abstract Multidrug resistant bacterial pathogens have become a serious global human health threat, and conjugative plasmids are important drivers of the rapid spread of resistance to last-resort antibiotics. Whereas antibiotics have been shown to select for adaptation of resistance plasmids to their...

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Bibliographic Details
Main Authors: Thibault Stalder, Linda M. Rogers, Chris Renfrow, Hirokazu Yano, Zachary Smith, Eva M. Top
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04662-0