Axon guidance of sympathetic neurons to cardiomyocytes by glial cell line-derived neurotrophic factor (GDNF).

Axon guidance of sympathetic neurons to cardiomyocytes by glial cell line-derived neurotrophic factor (GDNF).

Molecular signaling of cardiac autonomic innervation is an unresolved issue. Here, we show that glial cell line-derived neurotrophic factor (GDNF) promotes cardiac sympathetic innervation in vitro and in vivo. In vitro, ventricular myocytes (VMs) and sympathetic neurons (SNs) isolated from neonatal...

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Bibliographic Details
Main Authors: Keiko Miwa, Jong-Kook Lee, Yoshiko Takagishi, Tobias Opthof, Xianming Fu, Masumi Hirabayashi, Kazuhiko Watabe, Yasuhiko Jimbo, Itsuo Kodama, Issei Komuro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23843937/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23843937/?tool=EBI

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