The Zinc-Finger Domain Containing Protein ZC4H2 Interacts with TRPV4, Enhancing Channel Activity and Turnover at the Plasma Membrane

The Zinc-Finger Domain Containing Protein ZC4H2 Interacts with TRPV4, Enhancing Channel Activity and Turnover at the Plasma Membrane

The Ca<sup>2+</sup>-permeable Transient Receptor Potential channel vanilloid subfamily member 4 (TRPV4) is involved in a broad range of physiological processes, including the regulation of systemic osmotic pressure, bone resorption, vascular tone, and bladder function. Mutations in the &...

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Bibliographic Details
Main Authors: Laura Vangeel, Annelies Janssens, Irma Lemmens, Sam Lievens, Jan Tavernier, Thomas Voets
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
TRPV4
protein–protein interaction
ZC4H2
Ca<sup>2+</sup> signaling
channel turnover
Online Access:https://www.mdpi.com/1422-0067/21/10/3556

Internet

https://www.mdpi.com/1422-0067/21/10/3556

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