Metformin treatment reduces motor and neuropsychiatric phenotypes in the zQ175 mouse model of Huntington disease

Huntington’s disease: Diabetes drug limits disease-related degeneration in mice Metformin, an existing drug for diabetes, shows promise in alleviating symptoms of early Huntington’s disease in mouse models. Huntington’s disease is a genetic disorder that results in the gradual deterioration of motor...

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Bibliographic Details
Main Authors: Ana Sanchis, María Adelaida García-Gimeno, Antonio José Cañada-Martínez, María Dolores Sequedo, José María Millán, Pascual Sanz, Rafael P. Vázquez-Manrique
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-019-0264-9