nAChRs mediate human embryonic stem cell-derived endothelial cells: proliferation, apoptosis, and angiogenesis.

Many patients with ischemic heart disease have cardiovascular risk factors such as cigarette smoking. We tested the effect of nicotine (a key component of cigarette smoking) on the therapeutic effects of human embryonic stem cell-derived endothelial cells (hESC-ECs).To induce endothelial cell differ...

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Bibliographic Details
Main Authors: Jin Yu, Ngan F Huang, Kitchener D Wilson, Jeffrey B Velotta, Mei Huang, Zongjin Li, Andrew Lee, Robert C Robbins, John P Cooke, Joseph C Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2737633?pdf=render