Effects of Huanglian-Jie-Du-Tang and its modified formula on the modulation of amyloid-β precursor protein processing in Alzheimer's disease models.

Effects of Huanglian-Jie-Du-Tang and its modified formula on the modulation of amyloid-β precursor protein processing in Alzheimer's disease models.

Huanglian-Jie-Du-Tang (HLJDT) is a famous traditional Chinese herbal formula that has been widely used clinically to treat cerebral ischemia. Recently, we found that berberine, a major alkaloid compound in HLJDT, reduced amyloid-β (Aβ) accumulation in an Alzheimer's disease (AD) mouse model. In...

Full description

Bibliographic Details
Main Authors: Siva Sundara Kumar Durairajan, Ying-Yu Huang, Pui-Yee Yuen, Lei-Lei Chen, Ka-Yan Kwok, Liang-Feng Liu, Ju-Xian Song, Quan-Bin Han, Lei Xue, Sookja K Chung, Jian-Dong Huang, Larry Baum, Sanjib Senapati, Min Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3966845?pdf=render

Internet

http://europepmc.org/articles/PMC3966845?pdf=render

Similar Items