Circulating CD4+CD161+ T lymphocytes are increased in seropositive arthralgia patients but decreased in patients with newly diagnosed rheumatoid arthritis.

Circulating CD4+CD161+ T lymphocytes are increased in seropositive arthralgia patients but decreased in patients with newly diagnosed rheumatoid arthritis.

Improved understanding of the immune events discriminating between seropositive arthralgia and clinical synovitis is of key importance in rheumatology research. Ample evidence suggests a role for Th17 cells in rheumatoid arthritis. We hypothesized that CD4+CD161+ cells representing Th17 lineage cell...

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Bibliographic Details
Main Authors: Paulina Chalan, Bart-Jan Kroesen, Kornelis S M van der Geest, Minke G Huitema, Wayel H Abdulahad, Johan Bijzet, Elisabeth Brouwer, Annemieke M H Boots
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3815125?pdf=render

Internet

http://europepmc.org/articles/PMC3815125?pdf=render

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