Forced degradation studies of ivabradine and in silico toxicology predictions for its new designated impurities

All activities aim to eliminate genotoxic impurities or/and protect the medicinal compounds against degradation. There is a need to monitor impurities from all classification groups, so that ivabradine forced degradation studies were performed. Ivabradine proved to be a quite durable active substanc...

Full description

Bibliographic Details
Main Authors: Piotr ePikul, Marzena eJamrógiewicz, Joanna eNowakowska, Weronika eHewelt-Belka, Krzesimir eCiura
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00117/full