Polymer coil–globule phase transition is a universal folding principle of Drosophila epigenetic domains

Polymer coil–globule phase transition is a universal folding principle of Drosophila epigenetic domains

Abstract Background Localized functional domains within chromosomes, known as topologically associating domains (TADs), have been recently highlighted. In Drosophila, TADs are biochemically defined by epigenetic marks, this suggesting that the 3D arrangement may be the “missing link” between epigene...

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Bibliographic Details
Main Authors: Antony Lesage, Vincent Dahirel, Jean-Marc Victor, Maria Barbi
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Epigenetics & Chromatin
Subjects:
Epigenetic domains
Polymer
Drosophila
Coil–globule
Phase transition
Online Access:http://link.springer.com/article/10.1186/s13072-019-0269-6

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http://link.springer.com/article/10.1186/s13072-019-0269-6

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