The Role of TPA I/D and PAI-1 4G/5G Polymorphisms in Multiple Sclerosis

The Role of TPA I/D and PAI-1 4G/5G Polymorphisms in Multiple Sclerosis

Background. Previous studies have shown impaired fibrinolysis in multiple sclerosis (MS) and implicated extracellular proteolytic enzymes as important factors in demyelinating neuroinflammatory disorders. Tissue-type plasminogen activator (t-PA) and its inhibitor (PAI-1) are key molecules in both fi...

Full description

Bibliographic Details
Main Authors: Maja Živković, Nada Starčević Čizmarević, Luca Lovrečić, Inge Klupka-Sarić, Aleksandra Stanković, Iva Gašparović, Polona Lavtar, Evica Dinčić, Ljiljana Stojković, Gorazd Rudolf, Saša Šega Jazbec, Olivio Perković, Osman Sinanović, Juraj Sepčić, Miljenko Kapović, Borut Peterlin, Smiljana Ristić
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2014/362708

Internet

http://dx.doi.org/10.1155/2014/362708

Similar Items