Molecular Mechanisms of Oligodendrocyte Injury in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

Molecular Mechanisms of Oligodendrocyte Injury in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

New evidence has emerged over the last decade indicating that oligodendrocyte injury in multiple sclerosis (MS) is not a single unified phenomenon but rather a spectrum of processes ranging from massive immune destruction to a subtle cell death in the absence of significant inflammation. Experimenta...

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Bibliographic Details
Main Authors: Roumen Balabanov, Jilpa Patel
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
pathology
oligodendrocytes
cell signaling
interferon regulatory factor 1
Caspase 1
Online Access:http://www.mdpi.com/1422-0067/13/8/10647

Internet

http://www.mdpi.com/1422-0067/13/8/10647

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