Controlled Measurement and Comparative Analysis of Cellular Components in E. coli Reveals Broad Regulatory Changes in Response to Glucose Starvation.

Controlled Measurement and Comparative Analysis of Cellular Components in E. coli Reveals Broad Regulatory Changes in Response to Glucose Starvation.

How do bacteria regulate their cellular physiology in response to starvation? Here, we present a detailed characterization of Escherichia coli growth and starvation over a time-course lasting two weeks. We have measured multiple cellular components, including RNA and proteins at deep genomic coverag...

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Bibliographic Details
Main Authors: John R Houser, Craig Barnhart, Daniel R Boutz, Sean M Carroll, Aurko Dasgupta, Joshua K Michener, Brittany D Needham, Ophelia Papoulas, Viswanadham Sridhara, Dariya K Sydykova, Christopher J Marx, M Stephen Trent, Jeffrey E Barrick, Edward M Marcotte, Claus O Wilke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004400

Internet

https://doi.org/10.1371/journal.pcbi.1004400

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