Aberrant Methylation and Reduced Expression of LHX9 in Malignant Gliomas of Childhood
High-grade gliomas (HGGs) of childhood represent approximately 7% of pediatric brain tumors. They are highly invasive tumors and respond poorly to conventional treatments in contrast to pilocytic astrocytomas, which usually are well demarcated and frequently can be cured by surgery. The molecular e...
Main Authors: | Valentina Vladimirova, Thomas Mikeska, Andreas Waha, Niels Soerensen, Jingying Xu, Patrick C. Reynolds, Torsten Pietsch |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2009-07-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558609800225 |
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