Aberrant Methylation and Reduced Expression of LHX9 in Malignant Gliomas of Childhood

High-grade gliomas (HGGs) of childhood represent approximately 7% of pediatric brain tumors. They are highly invasive tumors and respond poorly to conventional treatments in contrast to pilocytic astrocytomas, which usually are well demarcated and frequently can be cured by surgery. The molecular e...

Full description

Bibliographic Details
Main Authors: Valentina Vladimirova, Thomas Mikeska, Andreas Waha, Niels Soerensen, Jingying Xu, Patrick C. Reynolds, Torsten Pietsch
Format: Article
Language:English
Published: Elsevier 2009-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558609800225